Follow signs from the airport to the Centrum for approximately 10km. You will pass the football stadium on the left and a large park open area on the right. At the next crossroad turn right to the tunnel. After the tunnel continue straight across the bridge. At the traffic lights turn left. Keep in the right lane while turning left and then turn right on traffic lights. Continue straight until the next tunnel. At the traffic lights turn right and continue to the second set of traffic lights, which are immediately after the next tunnel. Turn right and drive past the Hilton hotel on your left through two sets of traffic lights, then turn right at the next set of lights. At the next junction turn left and follow the road right to the next road junction. The Prague Marriott Hotel is situated across the street on your left hand side.