Ankeny hotel located near the I-80/I-35 East Mix Master. This Ankeny Marriott Hotel is located in Ankeny, Iowa off Interstate 35 north of Interstate 80 Between Des Moines and Ames. Just down the street from John Deere, Tones Spices, Albaugh Inc. and Casey’s General Stores HQ. Minutes from Adventure Land, Prairie Meadows Casino, and the Iowa State Fair grounds.. Iowa State University and the Des Moines International Airport are both just minutes away. If you are in town on business, or here for one of our sporting events, such as The Iowa High school wrestling tournament, or the boy or girls state basketball, or just here to relax, you can enjoy some of our great local attractions, which are all a short drive away, such as Bass Pro Shop, the Iowa Events Center and Wells Fargo Arena. The Science Center of Iowa and the Botanical Center are two other popular attractions. Enjoy shopping at Jordan Creek Town Center, the largest mall in Iowa.