Retreat to our well-appointed Houston Medical Center hotel

Marriott Rewards Category 7 · Points needed per night

Discover why the Houston Marriott Medical Center/Museum District is a preferred choice among hotels near the Texas Medical Center. Situated steps from leading hospitals, research centers and clinical facilities, including M.D. Anderson Cancer Center, our hotel ensures travelers enjoy a restful, relaxing stay. It begins with our refreshed, modern accommodations, all of which feature the latest in technology. After a restful night's sleep, stop by Driscoll's, our signature restaurant, for a hearty breakfast buffet before exploring the local area. Situated in downtown Houston, we're ideally located near the Museum District, Rice University and NRG Stadium. A premier destination for events, meetings and weddings, our hotel also features over 8,700 square feet of sophisticated venue space in Houston's city center. Whether you are traveling to the area for an extended-stay business trip or taking a weekend getaway, the Houston Marriott Medical Center/Museum District looks forward to welcoming you.

Show More

Guest Reviews

Confirmed Guest Reviews
4.4 out of 5.0
Cleanliness
4.6
Service
4.6
92% of guests recommend this hotel

Hear from our guests about their stay from 585 confirmed guest reviews

Key Amenities

  • Fitness center
  • Pool
  • Kitchen/kitchenette
  • Meeting event space

Highlights

  • Visit local attractions like the Houston Museum District, Rice University, the Houston Zoo and NRG Stadium from our hotel.

    Learn more
  • Take advantage of superb hotel amenities like two restaurants, a full fitness center and an indoor pool in the heart of downtown Houston, Texas.

    Learn more
  • Benefit from our superb location near the Texas Medical Center's array of leading hospitals and clinics, including the M.D. Anderson Cancer Center.

    Learn more

Guest Rooms

Stretch out in our stylish downtown Houston hotel

A woman traveling on boat

Let us spark your curiosity

Introducing the new TravelBrilliantly.com, a digital magazine offering stories that will spark new ways of thinking and broaden your perspective.

Read our digital magazine
TED Talk lightbulb

Reinventing the everyday

Learn about clever people solving common problems. Our first TED Inspiration article takes a deep dive into inventions inspired by reinvention.

Read this article

Check Room Rates & Availability

Houston Marriott® Medical Center/Museum District