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The Inn at Mayo Clinic

4420 Mary Brigh Drive  Jacksonville  Florida  32224  USA 

Check Rates & Availability

(proof of eligibility required at check-in)

About special rates

To make reservations by phone, call 1-800-331-3131 in the USA and Canada (or any of our worldwide reservation telephone numbers).

Our best rate. Guaranteed.

It Pays to Book Direct™

See guarantee terms

Our best rate. Guaranteed.

It Pays to Book Direct™

See guarantee terms

Thrive on long-stays

The Inn at Mayo Clinic Marriott has perfected the extended stay experience. By combining all the comforts of home with a passion for service, we strive to make every guest feel welcome. Our hotel is directly connected to the Mayo Clinic & provides comfort in 78 spacious studio, 1 and 2 bedroom suites. No detail is overlooked, from full kitchens with granite countertops & stainless steel appliances, to a free hot breakfast buffet each morning. Other complimentary services abound, like high speed wireless internet, grocery pickup and delivery, wheelchair assistance and an on-campus shuttle. Just 4 miles from Jacksonville Beach and convenient to major attractions, this unique Jacksonville, Florida hotel also offers an onsite fitness center for your enjoyment. Come experience the comforts of home in our The Inn at Mayo Clinic Suites. For those guests with special needs, rooms with walk in showers are available. This hotel does not participate in the Marriott Rewards Program or accept Bonus Bucks/Gift Cards.

Key Amenities

  • Free high speed Internet
  • Free breakfast
  • Kitchen/kitchenette
  • Fitness center

Map & Local Area


  • With our new and improved complimentary wireless Wi-Fi serivce throughout the hotel and increased speed of access, you can stay connected.
  • Near major attractions, recreation, beaches, universities, military bases and corporations.
  • For those guests with special needs, rooms with roll-in or walk-in showers can be requested.

When You Book On

Only pay when you stay

Avoid upfront payments.

Exclusions apply

Change your mind

Modify or cancel your reservation

Exclusions apply

Your room, your way

Request room extras when you book.

Conditions apply

It Pays to Book Direct™

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