All-suite Durham hotel near Duke University Medical Area

Marriott Rewards Category 5 · Points needed per night

Among Durham hotels, the Residence Inn Duke University Medical Center offers all of the comforts you desire and the ideal location less than 1 mile to Duke University, 2 miles to Duke University Medical Center and minutes to Durham Performing Arts Center (DPAC), NC Central University (6 miles) and UNC-Chapel Hill (8 miles). This Durham hotel provides easy highway access to Raleigh, Durham and Chapel Hill, NC. We have perfected the extended-stay experience by blending superior service with great value that includes spacious apartment-style suites with full-size kitchens, separate living areas, HDTVs and free Wi-Fi. Kitchens include large refrigerator, microwave, dishwasher, stove, coffee maker, and more. Re-energize in our 24-Hour fitness center, take a dip in our heated indoor pool, and start your day with a free hot breakfast buffet. Our hotel is perfect for staying 5+ nights or short-term stays. Reserve a suite today and experience a new kind of extended stay in Durham, NC!

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Guest Reviews

Confirmed Guest Reviews
4.8 out of 5.0
98% of guests recommend this hotel

Hear from our guests about their stay from 223 confirmed guest reviews

Key Amenities

  • Free high-speed internet
  • Free breakfast
  • Pet friendly
  • Kitchen/kitchenette


  • Our Duke Medical Center hotel features a large, fully-equipped fitness center and saline indoor pool.

  • Enjoy a free hot breakfast buffet and a full bar, serving up draft beers, wine and cocktails in the evenings.

  • Spacious suites with free Wi-Fi, full kitchens and separate living, working, and sleeping areas.

Visiting Duke University Hospital?

Our extended stay hotel is ideal for Duke Hospital Patients and Visitors!

Guest Rooms

Experience the style & charm of our all-suite Durham hotel

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Residence Inn® by Marriott® Durham McPherson/Duke University Medical Center Area