Hotel Republic San Diego, Autograph Collection

421 West B Street, San Diego, California 92101 USA
+1 619-398-3100

Pamper yourself with a renewing stay at our San Diego hotel

Rewards Category 5 Points needed per night

With a distinctive blend of modern convenience and boutique sophistication, Hotel Republic San Diego, Autograph Collection has everything you need for an unforgettable coastal California getaway. With our convenient location, you can embrace excitement just steps from our hotel. Dance the night away among Victorian architecture at Gaslamp Quarter, a premier entertainment district, and explore the vibrant restaurant scene in Little Italy just blocks away. Settle in our serene accommodations, boasting flat-screen TVs, sleek workstations and sweeping views of downtown San Diego. When hunger calls, delight in the convenience of room service, or indulge in flavorsome cuisine and refreshing cocktails at our two restaurants. During downtime, work up a sweat at our fully equipped 24-hour center. When it comes to your event needs, our elegant ballroom and outdoor venues create the perfect backdrop for your wedding reception or business conference. At Hotel Republic San Diego, Autograph Collection, escape the ordinary.

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Guest Reviews

4.4 out of 5.0
91% of guests recommend this hotel

Hear from our guests about their stay from 397 confirmed guest reviews

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Key Amenities

  • Pet friendly
  • Fitness center
  • Meeting event space


  • Begin your next business relationship or your happily-ever-after in our elegant venues, complete with customized catering and versatile AV equipment.

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  • End your coastal evenings with Baja-inspired cuisine and refreshing cocktails at our stylish, open-air restaurant, Topside Terrace Kitchen & Bar.

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  • Seamlessly seek your next adventure with our ideal location near Gaslamp Quarter, Little Italy, San Diego Bay and San Diego International Airport.

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Guest Rooms

Lounge in luxury at our downtown San Diego hotel

Autograph Collection Hotels

Exactly Like Nothing Else

Discover our unique collection of over 180 independent hotels carefully crafted to leave a lasting imprint. Because it’s what we collect, that makes us who we are. Let our collection add to yours.

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