In this Central American city, sophisticated culture meets tropical wildlife.

Panama City, Panama, is known as Central America’s cosmopolitan mecca, where modern high-rises mix with colonial architecture. From exploring the city’s diverse mix of Spanish, African and Native American cuisines to wandering heritage sites, this metropolis offers an eclectic range of sophisticated destinations and cultural activities. And when you want to escape, the lush jungles and scenic beaches that surround Panama City are a welcome respite.

See More
See Less

Explore Panama City

  • Bella Vista
  • Casco Viejo
  • Punta Paitilla

Bella Vista


By day, explore the diverse range of restaurants and shops that line this central Panama City neighborhood. But once the sun sets, Bella Vista is transformed into a hub for nightlife, with dance clubs, swank bars and lounges around every corner.

Known For

Shopping, Dining, Casinos, Nightlife, Entertainment

See More See Less

Casco Viejo


The storied and traditional streets of old Panama City are lined with colonial-era structures, baroque churches and charming local shops. While much of the city has undergone modern renovations, you can get a sense of the its multilayered history in Casco Viejo.

Known For

History , Museums, Restaurants , Architecture , Culture

See More See Less

Punta Paitilla


Punta Paitilla captures the cosmopolitan side of Panama City, with contemporary architecture, luxury shopping and fine dining stretching toward the bay. From sweeping skyline views to refreshing cocktails, this neighborhood gives you a taste of the good life.

Known For

Parks, Shopping Malls, Restaurants , Bars

See More See Less
Nearby Hotels and Resorts

Stay in The Center of it All

Immerse yourself in your destination at these centrally located hotels.

Showing 1-9 of 15 Hotels in Panama City1-9 of 15 Hotels

Explore the Rich History and Culture of Panama City, Panama

Middle eastern or Arabic dishes and assorted meze, concrete rustic background

Visit a UNESCO World Heritage Site

Get acquainted with the city by touring a museum dedicated to Panama’s unique influence on migration as well as a UNESCO World Heritage archaeological site. Experience the region's biodiversity close-up at the Tropical Research Institute and end your day with innovative dishes and seasonal cocktails. 

Colorful historic architecture

Explore Casco Viejo

Spend your second day immersed in the rich history of Panama City by way of Casco Viejo (“Old Quarter”). Browse the artisan boutiques and centuries-old cathedrals that line the streets of this hip neighborhood before a luxurious dinner at a tiny, critically acclaimed restaurant.

Aerial view of the Panama Canal

Take a Ride Through the Panama Canal

Complete your weekend with a quintessential ride along the Panama Canal. Guided tours will give you insight into both the design and history of the canal, while serving breakfast and lunch as you cruise. Finish the trip with a sumptuous seven-course tasting meal and craft cocktails. 

Experience More, Spend Less