Welcome to Aloft St. Louis Cortex

Newest Hotel in Cortex Community

A vibrant, bold, and energized experience in the heart of the Cortex Innovation Community is awaiting you. DIFFERENT BY DESIGN. Aloft hotels are open in space and spirit. Wake up to our ReFuel; cooked to serve breakfast to start your morning off before exploring popular attractions; Gateway Arch, Busch Stadium, Botanical Gardens, Anheuser-Busch Brewery, St. Louis Zoo, Science Center, Forest Park, Chaifetz Arena, Fox Theater, St. Louis University, Washington University, Harris Stowe State University, and A.T. Still University; all within a 5 mile radius, and conveniently located within a mile of Barnes Jewish Hospital, University of Health Sciences & Pharmacy, and The Grove. Our pet-friendly guest rooms are open in space and spirit. Connect to free high-speed Wi-Fi or mix and mingle, and sip on crafted signature cocktails at the open-air WXYZ® bar. Whether traveling for business or leisure; discover a perfect destination in Aloft St. Louis Cortex.

Rooms & Suites


Check-in: 3:00 pm

Check-out: 12:00 pm

Minimum Age to Check In: 21

Smoke Free Property

Pet Policy

Pets Welcome

2 Pets up to 40lbs each allowed per room with 20 USD pet fee per night per pet


Non-refundable pet fee Per Night: $20

Maximum pet weight: 40lbs

Maximum Number of Pets in Room: 2

Off-Site Parking
Cortex Orange Parking Garage - 4217 Custom Steel Dr. St. Louis, MO 63110 .2 Miles
Electric Car Charging Station
Additional Parking Information
Shuttle available to and from the garage -Contact hotel at 314-639-0050 once you arrive at the garage to arrange pick up

At This Hotel

Fitness Center

Re:charge Gym


Aloft St. Louis Cortex

4245 Duncan Avenue, St Louis, Missouri, USA, 63110

Tel: +1 314-639-0050
Distance from Property: 12.7 Miles
Phone Number: +1 314-890-1333
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Alternate Airport Transporation
Distance from Property: 14.4 Miles
Phone Number: +1 636-532-2222
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Alternate Airport Transporation


Bus Station

Central West End Transit Center

Subway Station


Property Details

Policies and Payments

Accepts: Credit Cards


Property has elevators

For more information about the physical features of our accessible rooms, common areas or special services relating to a specific disability please call +1 314-639-0050

Accessible Hotel Features

Property has elevators

Self Operating lift or a sloped entry in hotel swimming pools

Service Animals are Welcome

Accessible Areas with Accessible Routes from Public Entrance

Accessible Entrance to On-Site Pool

Entrance to On-Site Business Center is Accessible

Entrance to On-Site Fitness Center is Accessible

Main Entrance is Accessible

Meeting Spaces are Accessible

On-Site Restaurants are Accessible

Room and Suites Access through the Interior Corridor

Guest Room Accessibility

Accessible Vanities

Adjustable Height Hand-Held Shower Wand

Bathtub Grab Rails

Bathtub Seat

Close Caption TV

Deadbolts on Guest Room and Suites Doors

Electronic Room Key

Flashing Door Knockers

Guest Room and Suites Doors Self-Closing

Hearing Accessible Rooms and/or Kits

Lever Handles on Guest Room Doors

Lowered Deadbolts on Guest Room Doors

Lowered Electrical Outlets

Lowered Night Guards on Guest Room Doors

Lowered Viewports in Guest Room Doors

Mobility accessible rooms

Non-slip Grab Rails in the Bathroom

Roll-in Shower

Safety Chains and/or Latches on Guest Doors

Toilet Seat at Wheelchair Height - Toilet for Disabled

Viewports in Guest Room and Suites Doors

Environmental Practices

Electric car charging