Abide by the bay at our hotel near San Diego Zoo

Rewards Category 5 · Points needed per night

Reside waterside in California's beach city, at Residence Inn San Diego Downtown! Sitting in the heart of Little Italy, our hotel near San Diego Airport put guests within reach of the area's most popular attractions including the Gaslamp Quarter, San Diego Harbor & more! Plus, with convenient features like complimentary shuttle service to & from the airport, your vacation starts as soon as you land. Make yourself at home in our Mission Bay San Diego hotel spacious suites & enjoy comfortable living areas, fully equipped kitchens, HDTVs with premium channels & cloud-like sofa beds for a sound night's sleep. Our fitness center is available to guests around the clock & our heated outdoor pool is open all year! Fuel up for the day with delicious & nutritious options at our complimentary breakfast or grab something to-go at our 24-hour market! In the evening, unwind with other guests over complimentary drinks & light fare at The Residence Inn Mix (Mon - Wed). Book our hotel near Little Italy San Diego today!

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Guest Reviews

4.5 out of 5.0
94% of guests recommend this hotel

Hear from our guests about their stay from 479 confirmed guest reviews

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Key Amenities

  • Free high-speed internet
  • Free breakfast
  • Pet friendly
  • Kitchen/kitchenette


  • Ease into vacation mode at our hotel near Little Italy San Diego with fully equipped kitchens, dining areas & separate living rooms!

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  • Fuel up for the day with hearty & healthy options at our complimentary breakfast then unwind in the evening at The Residence Inn Mix (Mon-Wed).

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  • Break a sweat with cardio equipment & free weights in the onsite fitness center then cool off in the outdoor pool at our hotel near San Diego Zoo.

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Guest Rooms

Discover relaxation at our hotel near SeaWorld San Diego

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Run Like A Local

Take time to explore. Residence Inn and Under Armour Connected Fitness have partnered to create mapped runs for you to enjoy during your next stay.


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Residence Inn® by Marriott® San Diego Downtown

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