Welcome to Hotel Republic San Diego, Autograph Collection

Experience a San Diego Hotel Near Little Italy

Seamlessly blending contemporary comfort and boutique sophistication, Hotel Republic San Diego Autograph Collection offers everything you need for an unforgettable coastal California getaway. Embrace excitement steps from our hotel, courtesy of our convenient location. Dance the night away among Victorian architecture at the Gaslamp Quarter, a premier entertainment district, and explore the vibrant restaurant scene in nearby Little Italy. After exploring the city, retreat to serene accommodations with flat-screen TVs, sleek workstations and sweeping views from our hotel in downtown San Diego, CA. When hunger strikes, delight in the convenience of room service or indulge in flavorsome cuisine and refreshing cocktails at our two restaurants. During your downtime, work up a sweat at our 24-hour fitness center. Elegant and flexible, our ballroom and outdoor venues create the perfect backdrop for your wedding reception or business conference. Our Gaslamp Quarter hotel invites you to escape the ordinary.

Stay Cool in San Diego this Summer
Escape to sunny and 75 with beautiful beaches, vibrant neighborhoods, and endless sunshine of San Diego! For a limited time, book two nights at our stylish hotel and enjoy the third night free over the weekend.
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Rooms & Suites

Hotel Republic offers guests breathtaking views from spacious hotel rooms and suites featuring amenities to enhance the guest experience.

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Dine in Style

Private Dining

Embrace San Diego's sunshine with an unforgettable event on the Veranda & Deck. This versatile outdoor space accommodates up to 215 guests and offers stunning views, perfect for social gatherings or breakout sessions.

open air benches and tables with fire pit

What to Expect

Plan and Prepare for Your Stay

Hotel Exclusives

Book Early and Save in San Diego

Start planning your San Diego getaway and save up to 20% when you book at least seven days in advance. Book now for your upcoming long weekend adventure or romantic escape.

Virtual Tour

Experience all that Hotel Republic San Diego has to offer through exciting drone video tours. Take a virtual tour through our hotel and meeting spaces, set up for the perfect meeting. Explore our downtown San Diego hotel in its entirety, from stunning meeting rooms to spacious outdoor dining and more.

Grand Patio

Local Events

Discover the best of San Diego with our central hotel near top local events, attractions, and beaches. Book your stay for easy access to downtown festivals, waterfront concerts, and family fun. Perfect for event-goers and weekend getaways alike.

Alquiler de bicicletas y motocicletas scooter

More Ways to Enjoy Your Stay

Fitness Center

Fitness

Fitness Center

Recharge with our modern onsite fitness center featuring a variety of cardio and weight equipment.

OUR LOCATION

GETTING HERE

Hotel Republic San Diego, Autograph Collection

421 West B Street, San Diego, California, USA, 92101

Tel: +1 619-398-3100
Entrance
Steps From Little Italy

Little Italy is a chic, pedestrian-friendly neighborhood known for its trendy cocktail bars, brewpubs, and bustling restaurant patios.

Property Details

Frequently Asked Questions