Relax at our Houston hotel in the Texas Medical Center

Rewards Category 5 · Points needed per night

Feel the pulse of Space City while staying at Houston Marriott Medical Center/Museum District. Our downtown hotel is just steps from world-renowned hospitals, research centers and clinical facilities including M.D. Anderson Cancer Center and Texas Children's Hospital. The Museum District, Rice University, Minute Maid Park and NRG Stadium are nearby. Settle into our modern accommodations with luxury bedding, marble bathrooms and flat-screen TVs with premium movie channels. Enjoy room service from Fresh Bites or savor classic American fare at Driscoll's, our signature restaurant serving a hearty breakfast buffet in addition to lunch and dinner. In downtime, head to our 24-hour fitness center or indoor pool to get in your daily exercise. If you're in town for a business or social gathering, take advantage of our premier event venue boasting 8,758 square feet of flexible space perfect for conferences, banquets, weddings and receptions. Let Houston Marriott Medical Center/Museum District exceed your expectations.

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Guest Reviews

4.4 out of 5.0
92% of guests recommend this hotel

Hear from our guests about their stay from 882 confirmed guest reviews

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Key Amenities

  • Fitness center
  • Pool
  • Kitchen/kitchenette
  • Meeting event space


  • Custom event menus, rentable AV equipment and professional planners are among the benefits of reserving our hotel's meeting space.

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  • After a successful day of conducting business or sightseeing, stop by our Paladora Lounge to enjoy a custom cocktail, beer, wine and light fare.

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  • Our concierge-level and PURE Hypo-Allergenic rooms afford you additional amenities to make your short or extended stay in Houston comfortable.

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Guest Rooms

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Houston Marriott® Medical Center/Museum District