Welcome to Houston Marriott Medical Center/Museum District

Explore the best of Houston from our freshly renovated hotel

Book your Houston hotel stay at Houston Marriott Medical Center / Museum District, ideally located four miles from downtown and six miles from the Galleria. Located next to Methodist Hospital, our pet friendly hotel in Houston, TX, is connected to the Texas Medical Center via skybridge. Enjoy a complimentary shuttle within two miles to destinations such as: Museum District, Rice Village, Rice University, MD Anderson and TMC facilities. Take the METRORail red line in front of the hotel to events at NRG Park or downtown Houston. Enjoy casual cuisine in Main & Green or relax for happy hour, craft cocktails and dinner in CURATE. Our hotel features Pure Wellness rooms that promote well-being by providing purified air, allergy-friendly bedding, and an environment free of irritants so you can rest better. Upgrade your stay to gain exclusive access to our M Club lounge. Our Houston hotel boasts a newly renovated lobby, 24-hour fitness center, and refreshed event space, perfect for meetings, galas and weddings.

Main & Green Daily Lunch Specials
From Monday to Friday, enjoy a different lunch special for just $18.99, including a drink. Healthcare workers with ID get 20% off. To-go orders welcome. Click to reserve a table.
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Rooms & Suites

Experience Our Exclusive M Club
With a wealth of amenities and a prime location in the Texas Medical Center, admission to our club is designed to elevate your hotel experience. Select a room with club access, or request the upgrade upon check-in.


Check-in: 4:00 pm

Check-out: 12:00 pm

Minimum Age to Check In: 18

Pet Policy

Pets Welcome

$50 pet fee per night.


Non-Refundable Pet Fee Per Stay: $50.00

Maximum Number of Pets in Room: 2


On-Site Parking

Daily: $22.00


Daily: $44.00

Additional Parking Information
Self-parking Scurlock Tower garage entrance: 6535 Main St. NO in & out privileges. In & Out privileges only for Valet.

More Ways to Enjoy Your Stay

Gym equipment in fitness center


Fitness Center

Fitness center is open 24/7 and features Peloton bikes and FitnessOnDemand.

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Whirl Pool



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Group of people chatting in a bar

Let Your Stay Take You Further

Broaden your experience with us, whether by deepening your knowledge of cocktails in our Greatroom or learning something new with Manchester United.

Marriott guests enjoying their dining experience

Food for Your Journey

Pick up a fresh snack on your way out or linger over a meal with us. From light bites to classics with a local twist, enjoy food that is familiar yet elevated beyond the expected.

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Stacked Marriott Hotels Pillows on Bed

Experience Marriott at Home

Bring thoughtfully chosen details from our home to yours, from our iconic Marriott Pillow to our bath and body collection.

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Take the Red Line METRORail
Our hotel is located on the Dryden/TMC stop. Learn more about taking the Red Line METRORail Service by clicking here.
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Our Location

Getting Here

Houston Marriott Medical Center/Museum District

6580 Fannin Street, (Driveway Entrance on 1730 Dryden Road), Houston, Texas, USA, 77030

Tel: +1 713-796-0080

A Virtual Tour of Elevated Comfort and Convenience

Welcome to a virtual journey through the Houston Marriott Medical Center/Museum District, where modern sophistication meets unparalleled convenience. Situated in the heart of Houston's cultural and medical hub, this hotel is a beacon of comfort and innovation.

Houston Medical Center Hotel


Houston Clean Pledge
Houston Clean Pledge
2021 Tripadvisor Travelers Choice
2021 Trip Advisor Travelers Choice Hotel

Property Details

Frequently Asked Questions