Find our Houston hotel near the Museum District

Rewards Category 5 Points needed per night

Book your downtown stay at Houston Marriott Medical Center/Museum District. Easily access the Texas Medical Center via the skybridge or take our complimentary shuttle to the zoo, museums, Rice University or other locations within two miles of the hotel. The METRORail red line is directly in front of the hotel, making it easy to travel throughout Houston. Meet friends for a meal or cocktails in Paladora or Driscolls, the hotel's on-site dining spots. Grab a quick workout in our 24-hour fitness center or take a swim in our indoor pool. Houston Marriott Medical Center/Museum District offers newly renovated meeting spaces and a grand ballroom to set the ideal scene for a variety of downtown events, including elegant weddings. Relax in spacious guest rooms with premium bedding, smart TVs and refrigerators. Upgrade to a suite for ultimate comfort or select a PURE allergy-friendly guest room for your stay in Houston.

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Guest Reviews

4.4 out of 5.0

Hear from our guests about their stay from 1197 confirmed guest reviews

Marriott Bonvoy™ Credit Cards

Marriott Bonvoy™ Credit Cards

Earn More Points & Enjoy Special Benefits

Key Amenities

  • Fitness center
  • Pool
  • Meeting event space
  • Parking


  • Walk from our hotel directly to the Texas Medical Center via our convenient skybridge.

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  • Streamline your hotel stay in Houston with our special medical patient rates and free shuttle service serving sites in downtown.

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  • Select one of our hotel's newly renovated meeting and event venues, with more than 8,700 square feet of space, for your downtown Houston affair.

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New Restaurant Concepts Coming Late 2021

Curate will be your spot for a relaxing atmosphere serving craft cocktails, extensive selection of wine and full dinner menu. District on Two will be your central meeting place for breakfast, lunch and dinner. New concepts coming late 2021.

Guest Rooms

Contemporary hotel in Texas Medical Center

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Let Your Mind Travel

Marriott Hotels celebrates curiosity, creativity and new perspectives. We know that when your mind can travel, inspiration follows. That's why we create spaces that allow you to see the world differently with room to think bigger.

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Reinventing the everyday

At Marriott Hotels we seek to offer moments of inspiration for our guests. That’s why we have partnered with TED to create experiences that fuel your curiosity and spark your imagination.


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