Sophisticated spaces await in Houston

Rewards Category 5 Points needed per night

Balance work and leisure at Houston Marriott Medical Center/Museum District. We're the ideal choice when you're visiting the Texas Medical Center next door to Rice University across the street. Our hotel also sits near the Houston Zoo, NRG Stadium and the Museum District. Easily reach downtown Houston via the METRORail red line. Meet with friends for breakfast at Driscoll's or unwind with an evening cocktail in our hotel's contemporary bar, Paladora Lounge. Our five event venues comprise almost 9,000 square feet of space and offer on-site catering and AV services. Host a conference or wedding of up to 600 guests in our well-lit Grand Ballroom. Stop by our 24-hour fitness center for a quick workout, then relax in our indoor pool. When you retire to your room, our sophisticated spaces include premium bedding, marble bathrooms, smart flat-screen TVs and large work desks. Upgrade to a concierge-level room for access to the M Club, serving complimentary breakfast. Travel brilliantly in Houston.

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Guest Reviews

4.5 out of 5.0
93% of guests recommend this hotel

Hear from our guests about their stay from 1090 confirmed guest reviews

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Key Amenities

  • Fitness center
  • Pool
  • Kitchen
  • Meeting event space


  • Find our hotel next to the Texas Medical Center and within two miles of the city's Museum District, home to the Museum of Natural Science and more.

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  • Step across the street and reach attractions throughout Houston, such as the Astrodome, via our city's METRORail transit system and bus lines.

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  • Our hotel's recently renovated meeting spaces include two flexible conference rooms, two stylish boardrooms and our 5,600-square-foot Grand Ballroom.

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Guest Rooms

Contemporary hotel living in Houston

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Let Your Mind Travel

Marriott Hotels celebrates curiosity, creativity and new perspectives. We know that when your mind can travel, inspiration follows. That's why we create spaces that allow you to see the world differently with room to think bigger.

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Reinventing the everyday

At Marriott Hotels we seek to offer moments of inspiration for our guests. That’s why we have partnered with TED to create experiences that fuel your curiosity and spark your imagination.


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