Residence Inn Jacksonville-Mayo Clinic Area

4905 San Pablo Road South

Jacksonville, Florida 32224 USA

Phone:+1 904-992-2040

Fax:+1 904-992-0860

Toll-free:+1 800-331-3131

Sales:+1 904-992-2040

Services & Amenities

All public areas non-smoking

Bar-B-Q and/or picnic area

Car Rental

Coffee in lobby

Coffee/tea in-room

Grocery shopping service

Housekeeping service twice per week

Laundry on-site

Laundry on-site, coin operated

Limousine service

Mobility accessible rooms

Safe deposit boxes, front desk

Valet dry-cleaning

Guest Room Information

General Room Amenities

  • Air conditioning
  • Alarm clock
  • Coffee maker/tea service
  • Crib/Play Yard
  • Individual climate control
  • Iron and ironing board
  • Pillows: down/feather
  • Pull-out sofa bed
  • Safe

Bathroom Amenities

  • Bathroom amenities
  • Hair dryer

Room Entertainment

  • Cable channel: CNN
  • Cable channel: ESPN
  • Cable channel: HBO
  • Cable/satellite TV
  • Color TV
  • Internet TV

Kitchen Amenities

  • Dishwasher
  • Microwave oven
  • Pots, pans, serving dishes
  • Refrigerator
  • Silverware
  • Stove
  • Table and chairs
  • Toaster
  • Toaster oven

Business Amenities

  • Electrical outlet: desk level
  • Phone feature: speakerphone
  • Phone feature: voice mail
Visit the Guest Rooms page for more information


Dining Services

Bar-B-Q and/or picnic area

Sundry/Convenience store

Free Breakfast

Hot breakfast, complimentary


Hotel Bar & Lounge

Grab a small bite or just enjoy one of our specialty cocktails, variety or beer & wines. Healthy smoothies available during breakfast hours.

Open for dinner Dress code: Casual

Fitness & Recreation


Biking trail (5 miles)

Boating (5 miles)

Bowling (8 miles)

Horseback riding (15 miles)

Jet-skiing (5 miles)

Jogging/fitness trail (5 miles)

Kayaking (5 miles)

Miniature golf (8 miles)

Sailing (5 miles)

Sauna (2 miles)

Scuba diving (5 miles)

Snorkeling (5 miles)

Volleyball (5 miles)

Water-skiing (5 miles)

Nature preserve, trail (8 miles)

Bike Rentals (5 miles)


Fitness center on-site


Outdoor Swimming Pool


(7.8 miles)

Local Attractions

Mayo Clinic

4500 San Pablo Road

St Johns Town Center Mall

4663 River City Dr.

TPC Sawgrass / PGA Tour

110 Championship Way


10531 Brightman Blvd

Alhambra Theater & Dining

12000 Beach Blvd

Baseball Grounds of Jacksonville

301 A Philip Randolph Blvd

Vystar Veterans Memorial Arena

300 A Philip Randolph Blvd

TIAA Bank Field / Stadium

1 TIAA Bank Field Dr.

Daily's Place Amphitheater

1 Daily's Place

Kathryn Abbey Hanna Park

500 Wonderwood Dr.

Florida Theatre

128 East Forsyth St. Ste 300

World Golf Hall of Fame

1 World Golf Place

Visit Local Area page for more information

Airport Information

Jacksonville International Airport (JAX)


Airport Phone: +1 904-741-4902

Hotel direction: 28.2 miles SE

This hotel does not provide shuttle service.

Visit JAX airport website
Driving directions

Get on I-95 S from Dixie Clipper Dr and Airport Rd. Take I-295 S and FL-202 E/Butler Blvd to San Pablo Rd S. Take the San Pablo Rd exit from FL-202 E/Butler Blvd. Take the San Pablo Rd exit. Turn right onto San Pablo Rd S. Make a U-turn. Destination will be on the right.

Jacksonville Executive at Craig Airport (CRG)


Airport Phone: +1 904-741-5066

Hotel direction: 11 miles SE

This hotel does not provide shuttle service.

Visit CRG airport website

Business Services

Copy service

Fax service

Fee for each additional page of outgoing fax

Fee for first page of incoming fax

Messenger service

Network/Internet printing

Overnight delivery/pickup



For more information about the physical features of our accessible rooms, common areas, or special services relating to a specific disability, please call +1 904-992-2040+1 904-992-2040.

Accessible Areas with Accessible Routes from Public Entrance

  • Concierge desk
  • Fitness Center
  • Meeting spaces and ballrooms
  • Pool accessible
  • Pool pathway
  • Public entrance alternative
  • Public restrooms
  • Registration Desk Pathway
  • Registration desk
  • Restaurant(s)/Lounge(s)

Accessible Hotel Features

  • Accessible Self-parking
  • Accessible transportation with advanced notice
  • Meeting room(s) with assistive listening devices
  • Self-parking facility, van-accessible spaces
  • Self-parking, accessible spaces
  • Service animals are welcome
  • Valet parking for vehicles outfitted for drivers in wheelchairs
  • Elevators

Guest Room Accessibility

  • Accessible guest rooms with 32” wide doorways
  • Accessible route from public entrance to accessible guest rooms
  • Alarm clock telephone ringers
  • Bathroom grab bars
  • Bathtub grab bars
  • Bathtub seat
  • Deadbolt locks, lowered
  • Door night guards, lowered
  • Doors with lever handles
  • Electrical outlets, lowered
  • Flashing door knockers
  • Hearing accessible rooms and/or kits
  • No transfer showers available
  • Roll-in shower
  • Shower wand, adjustable
  • TTY/TTD available
  • TV with close-captioning
  • Toilet seat at wheelchair height
  • Vanities, accessible
  • Viewports, lowered
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