Residence Inn Jacksonville-Mayo Clinic Area

Welcome to Residence Inn Jacksonville-Mayo Clinic Area

A New Level of Comfort, Well Being and Hospitality

The beautiful Residence Inn Jacksonville - Mayo Clinic Area is uniquely positioned and customer focused, providing a clean & comfortable environment featuring an array of amenities and special care services. Located less than 1 mile from the Mayo Clinic, a complimentary hourly shuttle from 7am-5pm is provided. Inquire about post-treatment nursing care partnership. When you want to explore Jacksonville, we're 3 mi to the Atlantic Ocean, 5 mi to University of North Florida, 6 mi to shopping at St. John’s Town Center and 17 mi to all the excitement in Downtown Jacksonville. Our suites feature a fully equipped kitchen, living area, free WiFi, sofabed, 50" or 55" SMART HDTV with Netflix. Relax with a dip in our heated outdoor swimming pool or enjoy a beverage and a bite to eat at our lobby bar. Get a great workout in our state-of-the art fitness center. Book your next event with us featuring 4,128 sq ft of flexible meeting and outdoor space for up to 120 people. We look forward to exceeding your expectations.

Plan Your TPC 2024 Visit
Experience the epitome of convenience during The Players Championship by staying at our hotel, where unmatched comfort and proximity to the event await you. Book your stay today!

Rooms & Suites


Check-in: 4:00 pm

Check-out: 11:00 am

Minimum Age to Check In: 21

Smoke Free Property

Pet Policy

Pets Welcome

Pets allowed with non-refundable fee of USD 150 per room per stay


Non-Refundable Pet Fee Per Stay: $150.00

Maximum Pet Weight: 50.0lbs

Maximum Number of Pets in Room: 2


Complimentary On-Site Parking

Long Term Parking

More Ways to Enjoy Your Stay

Fitness Center Equipment


Fitness Center

24 Hour Fitness Center with an array of equipment, machines, and free weights,

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Outdoor Pool


Outdoor Swimming Pool

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Wellness Through Hospitality Specialized for our guests

Your wellness is important to us. View offerings with our in-suite care partner as well as additional wellness items throughout our hotel

Package Handling Fees
Please note that for all packages received for guests before the scheduled arrival date, we will be charging a $5.00 per package per day fee.


Residence Inn Jacksonville-Mayo Clinic Area

4905 San Pablo Road South, Jacksonville, Florida, USA, 32224

Tel: +1 904-992-2040

Property Details

Frequently Asked Questions