Palacio del Inka, a Luxury Collection Hotel, Cusco

A storied mansion dating back nearly five centuries, Palacio del Inka stands in the historic center of Cusco. Directly across from the Koricancha (Temple of the Sun), it is a five-minute walk from the main square and less than a mile from an array of museums, markets and restaurants. The 154 standard guest rooms feature coffered niches of dark wood, while maroon entry halls with yellow ochre walls mirror colors in the Damascus figures of the floor carpeting. Meanwhile, the 17 Casa de los Cuatro Bustos Suites, all with 13-foot ceilings, have particularly rich textiles in addition to classic decorative pieces, lounge chairs, hand carved chests and writing desks to recreate the feel of a Colonial Cusco mansion. Uniting the past and present, Andes Spirit Spa presents indigenous treatments and an indoor therapy pool. Meanwhile, Inti Raymi Restaurant offers authentic Peruvian dishes, while a variety of meeting and event venues invite guests to host an enchanting occasion.