Welcome to Rochester Marriott Mayo Clinic Area

Find us downtown near the Mayo Clinic

Directly connected to the Mayo Clinic, Rochester Marriott Mayo Clinic Area, hotel offers easy access to some of the city's most popular attractions via climate-controlled pedestrian walkways and skyways. Shop at University Square and enjoy biking, fishing and horseback riding nearby. Or visit Minneapolis and Saint Paul, an easy day trip from Rochester, MN. Host an event or board meeting in our hotel's modern venues or unwind after a busy day at Salute Wine Bar & More. Business travelers, enjoy spacious guest rooms with well-lit work areas and complimentary Wi-Fi. All our newly renovated rooms and suites feature luxurious bedding and HDTVs, plus a wealth of upscale amenities. Find modern luxury near downtown Rochester at Rochester Marriott Mayo Clinic Area.

Rooms & Suites


Check-in: 4:00 pm

Check-out: 12:00 pm

Minimum Age to Check In: 18

Smoke Free Property

Pet Policy

Pets Not Allowed

No pets allowed-service animals only

Off-Site Parking
Kahler Grand Hotel parking garage (valet also available for $25/night) .1 Miles


Daily: $25

Additional Parking Information
Parking is offsite in nearby Kahler Grand Hotel parking garage / Parking available for non-registered guests


Plan and Prepare for your Stay

At This Hotel

Fitness Center

Fitness Center

Socialize in Style

Elevated, modern spaces to connect with friends, family and colleagues.

Journey to Something Wonderful

Elevate your natural curiosity. We’ve partnered with TED for experiences with limitless discovery.

Learn More
Stacked Marriott Hotels Pillows on Bed

Bring the Marriott Experience Home

Our hotels are designed with you in mind and your home can be too. Create a space for rest and relaxation with our iconic Marriott Pillow, This Works bath and body collection and our premium bed and bedding set.

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Our Location

Getting Here

Rochester Marriott Mayo Clinic Area

101 First Avenue SW, Rochester, Minnesota, USA, 55902

Tel: +1 507-280-6000
Distance From Property: 8 Miles
Phone Number: +1 507-282-2328
Visit Website
Alternate Airport Transportation:
GO Rochester Direct
Distance From Property: 70 Miles
Phone Number: +1 612-726-5800
Visit Website
Alternate Airport Transportation:
GO Rochester Direct


Bus Station:

Rochester City Lines

Train Station:



2021 Trip Advisor Travelers Choice Hotel
2021 Trip Advisor Travelers Choice Hotel
2017 Trip Advisor Green Partner Logo
2017 Trip Advisor Green Partner Logo

Property Details

Policies and Payments

Accepts: Credit Cards


Concierge desk service

Property has elevators

Vending Machine

For more information about the physical features of our accessible rooms, common areas or special services relating to a specific disability please call +1 507-280-6000

Accessible Hotel Features

Property has elevators

Self Operating lift or a sloped entry in hotel swimming pools

Service Animals are Welcome

Accessible Areas with Accessible Routes from Public Entrance

Accessible Entrance to On-Site Pool

Entrance to On-Site Business Center is Accessible

Entrance to On-Site Fitness Center is Accessible

Main Entrance is Accessible

Meeting Spaces are Accessible

On-Site Restaurants are Accessible

Room and Suites Access through the Interior Corridor

Guest Room Accessibility

Accessible Vanities

Adjustable Height Hand-Held Shower Wand

Alarm Clock Telephone Ringers

Bathtub Grab Rails

Bathtub Seat

Close Caption TV

Deadbolts on Guest Room and Suites Doors

Electronic Room Key

Flashing Door Knockers

Guest Room and Suites Doors Self-Closing

Hearing Accessible Rooms and/or Kits

Lever Handles on Guest Room Doors

Lowered Deadbolts on Guest Room Doors

Lowered Electrical Outlets

Lowered Night Guards on Guest Room Doors

Lowered Viewports in Guest Room Doors

Mobility accessible rooms

Non-slip Grab Rails in the Bathroom

Roll-in Shower

Room Windows Open

Safety Chains and/or Latches on Guest Doors

Secondary Locks on Room Windows

TTY/TTD Compatible

Toilet Seat at Wheelchair Height - Toilet for Disabled

Viewports in Guest Room and Suites Doors


TripAdvisor GreenLeaders Certified


Carbon Footprint: 22.72 kg per room night

Water Footprint: 325.47 liters per room night