Book your adventure at our Panama City hotel and golf resort

Rewards Category 5 Points needed per night

The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City has prepared a thrilling vacation for you and your loved ones. Our urban resort has a heated pool with a luxurious setting, five on-site restaurants and a Jack Nicklaus-designed golf course. If you want to venture out, Cincuentenario Avenue and Costa del Este Panama are close by. We're also located within 9 miles of Tocumen International Airport. Settle into a hotel room with an inspiring golf course view, and filled with soothing Le Chemin amenities. Spend a day of relaxation at our spa, which offers couple's massages and facials. The infinite beauty of our property makes it perfect for important gatherings, whether wedding or business related. Event venues are available both indoors and outdoors, with our Grand Salon being the largest and most luxurious space. Get ready for a greatly satisfying stay at The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City. We'll provide outstanding service every step of the way.

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Sunset Golf Course

Friday, March 5, 2021

A Noteworthy Golf Course

Guest Reviews


out of


99% of guests recommend this hotel

Our Signature Suites

Executive Suite with Golf  View
Master Suite Living Room

A Destination Spa

Inspired by Panama’s rich culture, tropical beauty and cosmopolitan spirit, The SPA at The Santa Maria Hotel & Golf Resort transports guests to new levels of health, wellness and relaxation.

Luxurious Meetings

Whether you are hosting an exclusive board meeting or a tech-savvy sales conference for up to 500 guests, The Santa Maria Hotel & Golf Resort offers an impressive venue for signature gatherings.

Meeting 5 and 6
Meeting Room
Golf Course

Discover Panama City

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